Biology

John McDonald, Professor and Chair

Ph.D., Genetics, University of California Davis, 1977
john.mcdonald@biology.gatech.edu
Phone: 404-894-3735, 404-385-6630
Fax: (404) 894-0519
Office: CE 201 / IBB 3314

Publications

Bowen, N., P. Wade and J. F. McDonald. (2006) The Role of Pax8 in the Mesenchymal to Epithelial Transition of Ovarian Mesothelium into Epithelial Ovarian Carcinomas. Gynecologic Oncology (in press).

Polavarapu, N., N. Bowen and J. F. McDonald 2006. Identification and characterization of chimpanzee LTR retrotransposons. J. Virology (in press).

Herrera, R. J. , R. Lowery, A. Alfonso, J. F. McDonald and J. Luis..( 2006). Ancient retroviral insertions among human populations. J. Human Genetics (in press).

Ganko, E., C. Greene, J. Lewis, V. Bhattacharjee and J. F. McDonald. (2006) LTR retrotransposon-gene associations in D. melanogaster. J Mol Evol. 62: 111-120.

De Barry. J., E. Ganko and J. F. McDonald. (2006). The contribution of LTR retrotransposons sequences to gene evolution in Mus musculus. Mol Biol Evol . 23: 479-481.

McDonald, J.F., Matzke, M.A. and A.J. Matzke. (2005). Host defenses to transposable elements and the evolution of genomic imprinting. Cytogenet Genome Res. 110: 242-249.

Franchini, L.F., E.W. Ganko, J.F. McDonald. 2004. Retrotransposon-gene Mol. Biol. Evol. 21(7):1323-1331. 2004

Menendez L, Benigno BB, McDonald JF. 2004. L1 and HERV-W retrotransposons are hypomethylated in human ovarian carcinomas. Mol Cancer., Apr 26;3(1):12.

Gao, L, McCarthy EM, Ganko EW, McDonald JF. 2004. Evolutionary history of Oryza sativa LTR retrotransposons: a preliminary survey of the rice genome sequences. BMC Genomics, 5:18. PubMed / Journal Website

McCarthy, E.M., and J.F. McDonald. 2004. LTR Retrotransposons of Mus musculus. Genome Biology, 5:R14.

Ganko, E.W., V. Bhattacharjee, P.Schliekelman, and J.F. McDonald. 2003. Evidence for the contribution of LTR retrotransposons to C.elegans gene evolution. Mol. Biol. Evol., 20(11):1925-1931.

McCarthy, E.M., and J.F. McDonald. 2003. LTR_STRUC: A novel search and identification program for LTR retrotransposons. Bioinformatics 19: 362-367.

Jordan, I.K., and J.F. McDonald. 2002. A biologically active family of human endogenous retroviruses (HERVs) evolved from an ancient inactive lineage. Genome Letters 1(2):105-109.

McCarthy, G., J. Liu, and J.F. McDonald. 2002. The LTR retrotransposons of Oryza sativa. Genome Biology 3:10.

McCollum, A., E.W. Ganko, P. Barrass, J. Rodriguez, and J.F. McDonald. 2002. Evidence for the adaptive significance of an LTR retrotransposon sequence in a Drosophila heterochromatic gene. BMC Evolutionary Biology 2 No. 5: 1-7.

Ganko, E., K.T. Fielman, and J.F. McDonald. 2001. Evolutionary history of Cer elements and their impact on the C.elegans genome. Genome Research 11:2066-2074.

Bowen, N., and J. F. McDonald. 2001. Drosophila euchromatic LTR retrotransposons are much younger than the host species in which they reside. Genome Research 11:1527-1540.

Promislow, D. L., I. K. Jordan and J. F. McDonald. 1999. Genome demography: a life-history analysis of transposable element evolution. Proc. R. Soc. Lond. B. 266: 1555-1560.

Jordan, I.K. and J. F. McDonald. 1999. Comparative genomics and evolutionary dynamics of Saccharomyces cerevisiae Ty elements. Genetica 107: 3-14.

Jordan, I.K. and J.F. McDonald. 1999. The role of interelement selection in Saccharomyces cerevisiae Ty element evolution. J. Mol. Evol. 49: 352-357.

Jordan, I.K. and J.F. McDonald. 1999. Tempo and mode of yeast retrotransposon evolution. Genetics 151: 1341-1351.

Jordan, I.K. and J.F. McDonald. 1999. Phylogenetic perspective reveals abundant Ty1/Ty2 hybrid elements in the Saccharomyces cerevisiae genome. Mol. Biol. Evol. 16: 419-422.

Jordan, I. K. and J.F. McDonald. 1999. Evidence for the recent horizontal transfer of an LTR retrotransposon. Proc. Natl. Acad. Sci., USA. 96: 12621-12625.

McDonald, J. F. 1999. Genomic imprinting as a co-opted evolutinary character. Trends in Ecol. Evol. 13:94-95.

Miller WJ, McDonald JF, Nouaud D, Anxolabehere D. 1999. Molecular domestication--more than a sporadic episode in evolution. Genetica, 1999;107(1-3):197-207.

Bowen, N. and J. F. McDonald. 1999. Genomic analysis of Caenorhabditis elegans reveals ancient families of retroviral-like elements. Genome Research 9:924-935.