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In August, Biology assistant professor Will Ratcliff and his collaborators received a three year, $562,000 NASA grant to investigate the origin and evolutionary consequences of multicellular life cycles. All multicellular organisms exhibit a characteristic life cycle that alternates between stages of reproduction, growth and development.
Posted on Aug 20 2015 - 6:08am.
In August, Biology Professor Yury Chernoff was awarded a 3 year NSF Molecular and Cellular Biology grant to investigate the control of heritable protein aggregation by ribosome-associated chaperones.
Posted on Aug 17 2015 - 10:26am.
A new study provides a perspective on the role that retrotransposable elements play in the precise execution of the human genome’s regulatory program. This study found that one particular class of RTEs – Mammalian-wide Interspersed Repeats (MIRs) – can serve as genetic landmarks that help to target specific regulatory mechanisms to a large number of genomic sites and thereby lead to the coordinated regulation of the genes located nearby these sites.
Posted on Aug 11 2015 - 10:22pm.
Since the classical studies of Jacob and Monod in the early 1960s, it has been evident that genome sequences contain not only blueprints for genes and the proteins that they encode, but also the instructions for a coordinated regulatory program that governs when, where and to what extent these genes and proteins are expressed. The execution of this regulatory code is what allows for the creation of very different cell- and tissue-types from the same set of genetic instructions found in the nucleus of every cell. A recent study published in PNAS (July 27, 2015) shows that critical aspects of this regulatory program are encoded by genomic sequence elements that were previously thought to be mere "junk DNA" with no important functions.
Posted on Aug 6 2015 - 12:30pm.