Brian Hammer
Associate Professor
Cherry Emerson 223
Cherry Emerson 218E 218F, 219A, 210
Educational Experience:
Ph.D., Microbiology and Immunology, University of Michigan Medical School, 2001, M.S., Conservation Biology, University of Michigan, 1995, B.S., Biology, Boston College, 1990
Research Interests:
bacterial genetics and genomics, signal transduction, biofilms, quorum sensing, small RNAs

The main focus of research in my lab is to understand how bacteria convert intracellular and extracellular chemical information into changes in gene expression. In Vibrio cholerae, a common inhabitant of aquatic ecosystems and the cause of the fatal disease cholera, we are taking a “top-down” approach by dissecting cell signaling networks that control behaviors important in the environment and human host. In the model organism, E. coli, we are taking a "bottom-up" approach by engineering signaling systems into this microbe toward a goal of rationally designing molecular-based communication systems. To achieve these ends we use complementary methods including genetics and genomics, biochemistry, bioinformatics, and ecological approaches.